Cell differentiation, cell growth and cancer

Dr Yuzuru Kubohara (Visiting Researcher, MRC Laboratory of Molecular Biology)

Saturday, 22 January, 2000; 7:30-9:30pm

Seminar room, Darwin College

Cell differentiation is one of the most conspicuous phenomena seen in the process of development in multicellular organism. Normally, cells are programmed to differentiate into specific cell types at proper ratio(s), communicating (interacting) with each other. The cell-to-cell interactions are often mediated by signal molecules and subsequent signal transduction systems. In contrast, cancer cells can be regarded as de-differentiated cells that have lost programmed properties or as cells that are unable to properly communicate with each other because of deficiencies in the signaling system. Therefore, the elucidation of the mechanism of cell differentiation involving signal transduction would provide important insights into cancer therapy.
In this seminar, I would like to explain ABC of cancer and introduce the latest frontiers of cancer biology and cancer therapy, that is, what is cancer, how medical doctors have treated it, and how scientists try to fight off cancer.